ISG Workshop 2026

Day 4 Historical overview, PLINK, LMM GWAS, RAP, METAL, rGE and assortative mating, within-family GWAS, interpretation Day 0 & Tech Support Preparation before the course. R tutorials, reading lists, and technical support documentation. Day 3 heritability, variance components, matrix approaches, IBD vs IBS, family and twin modeling Day 5 prediction theory, ROC analysis, polygenic risk scores, SBayesRC, G×E applications Day 6 genetic correlations, LD-score regression, Genomic SEM Day 8 rare variants, fine mapping, TWAS, omics integration, cross-ancestry and AI-based prediction Day 1 biometrical modeling; population genetics; data sources; ethics and historical context; simulations and PCA Day 7 causal inference, Mendelian randomization (univariate and multivariate), longitudinal and family-based designs, genetic confounding Day 2 assumptions, QC, imputation, PLINK and R basics, phenotype distributions, and transformations