do MR results translate well to other ancestries? is there a way to avaluate that?
https://www.researchsquare.com/article/rs-6091701/v1
Replying to “do MR results translate well to other ancestries? …”:
In general, you want your MR studies to be ancestral homogenous. Unmodelled population stratification can produce all sorts of problems in MR studies. There are more advanced MR models that try to model ancestral differences and capitalize on this (Daniel has listed an example in the chat below).