# Relatedness and GRM

**URL:** https://isgw-forum.colorado.edu/t/relatedness-and-grm/646
**Category:** Theory & background
**Created:** [April 29, 2024, 7:13am UTC](https://isgw-forum.colorado.edu/t/relatedness-and-grm/646 "2024-04-29T07:13:11Z")
**Posts on this page:** 1
**Page:** 1

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### Author: ![soumej53](https://isgw-forum.colorado.edu/user_avatar/isgw-forum.colorado.edu/soumej53/32/561_2.png) [@soumej53](https://isgw-forum.colorado.edu/u/soumej53)
#### Post date: [April 29, 2024, 7:13am UTC](https://isgw-forum.colorado.edu/t/relatedness-and-grm/646/1 "2024-04-29T07:13:11Z")

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Hello,  
I wanted to ask if including grm in mixed model GWAS would be sufficient enough to adjust related individuals (first, second, third degree individuals) or is one recommended to remove the obviously related individuals and apply grm as random effect to adjust merely cryptic relatedness?  
Thanks a lot