I was wondering if in the following scenario would sample-size weighting be used - meta-analysis of phenotypes combining cohorts of PTSD severity and and PTSD case-controls. Or would inverse-weighting be used? And why?
I would agree that in this case (the phenotypes are fairly different) sample-size weighting is more reasonable than the other.
there are methods for combining case:control and continutious traits of the same construct - look at the Waters ADHD PGC papers