HWE and selection

Is it ever possible that deviations from HWE are actually not a problem, but a signal of selection occurring for or against a phenotype? My intuition is that the kinds of timescales required to generate such a deviation would have to be so long that it’s unlikely, but curious if anyone has thoughts on this.

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HI Calen - good question! Can you repost this under the Association channel? This channel was for last year’s workshop…

Ok trying to figure out how to do that. Sorry!