# Day 2

**URL:** https://isgw-forum.colorado.edu/c/isg-workshops-2022/day-2/14.md

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## [About the Day 2 category](https://isgw-forum.colorado.edu/t/about-the-day-2-category/34)

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**Author:** [@JML](https://isgw-forum.colorado.edu/u/JML)\
**Replies:** 5\
**Last updated:** [June 7, 2022, 1:13pm UTC](https://isgw-forum.colorado.edu/t/about-the-day-2-category/34 "2022-06-07T13:13:26Z")

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ACE models with pihat, Binary/Ordinal Data, Power

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## [Power to Detect E and r(e)](https://isgw-forum.colorado.edu/t/power-to-detect-e-and-r-e/385)

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**Author:** [@ColinFreilich](https://isgw-forum.colorado.edu/u/ColinFreilich)\
**Replies:** 2\
**Last updated:** [September 15, 2022, 5:28pm UTC](https://isgw-forum.colorado.edu/t/power-to-detect-e-and-r-e/385 "2022-09-15T17:28:45Z")

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Hi all, I was wondering if anyone had resources for detecting unique environmental variance and unique environmental correlations. I think I understand why this is not possible using the weighted noncentrality parameter…

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## [Standardization](https://isgw-forum.colorado.edu/t/standardization/372)

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**Author:** [@hallerl1](https://isgw-forum.colorado.edu/u/hallerl1)\
**Replies:** 2\
**Last updated:** [July 15, 2022, 12:56am UTC](https://isgw-forum.colorado.edu/t/standardization/372 "2022-07-15T00:56:00Z")

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Hi, I was wondering if there is a preference with regards to standardizing a phenotypic (continuous) variable when running a classical twin design and sex-limited twin design? Does the variable need to be standardized t…

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## [Ordinal Data—standardized thresholds](https://isgw-forum.colorado.edu/t/ordinal-data-standardized-thresholds/322)

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**Author:** [@JuanJMV](https://isgw-forum.colorado.edu/u/JuanJMV)\
**Replies:** 4\
**Last updated:** [June 20, 2022, 3:34pm UTC](https://isgw-forum.colorado.edu/t/ordinal-data-standardized-thresholds/322 "2022-06-20T15:34:08Z")

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Hello all, I have a question about ordinal data analysis. I would like to fit a univariate model (1 ordinal variable with 3 categories) in two cohorts (cohort 1 and cohort 2) allowing for sex differences. If I am not wr…

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## [Day2 practical answers pdf and video](https://isgw-forum.colorado.edu/t/day2-practical-answers-pdf-and-video/354)

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**Author:** [@JessicaTodorov](https://isgw-forum.colorado.edu/u/JessicaTodorov)\
**Replies:** 3\
**Last updated:** [June 17, 2022, 1:57am UTC](https://isgw-forum.colorado.edu/t/day2-practical-answers-pdf-and-video/354 "2022-06-17T01:57:45Z")

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Hi Katrina, I am looking for day 2 practical answers and the video walking us through the practical. Could you direct me to where I can find these? Thank you! Jessica

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## [Parental alleles informative vs ambiguous](https://isgw-forum.colorado.edu/t/parental-alleles-informative-vs-ambiguous/301)

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**Author:** [@anonymous7](https://isgw-forum.colorado.edu/u/anonymous7)\
**Replies:** 2\
**Last updated:** [June 10, 2022, 11:19am UTC](https://isgw-forum.colorado.edu/t/parental-alleles-informative-vs-ambiguous/301 "2022-06-10T11:19:40Z")

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Can you discuss further the inheritance of parental alleles that are informative vs non-informative/ambiguous? It appears that inheriting non-ambiguous alleles are those that would not bond on complementary strands. Than…

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## [K0 k1 k2 calculation (Video2 Slide10)](https://isgw-forum.colorado.edu/t/k0-k1-k2-calculation-video2-slide10/312)

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**Author:** [@evora](https://isgw-forum.colorado.edu/u/evora)\
**Replies:** 1\
**Last updated:** [June 9, 2022, 6:38am UTC](https://isgw-forum.colorado.edu/t/k0-k1-k2-calculation-video2-slide10/312 "2022-06-09T06:38:47Z")

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Hello, it might be a nerd question. But may I ask for an intuitive way to calculate k0 k1 k2 by hand between different relatives with different relatedness? Or maybe a recommendation of the reference of any textbook/tu…

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## [Degrees of freedom in the binary model](https://isgw-forum.colorado.edu/t/degrees-of-freedom-in-the-binary-model/318)

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**Author:** [@katrina](https://isgw-forum.colorado.edu/u/katrina)\
**Replies:** 1\
**Last updated:** [June 8, 2022, 9:05pm UTC](https://isgw-forum.colorado.edu/t/degrees-of-freedom-in-the-binary-model/318 "2022-06-08T21:05:55Z")

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There was a group in Session B who noticed that the degrees of freedom in the binary model was not adding up. Or rather adding up to being too high. This has been tracked down (thank you Mike Hunter) to an issue in C++ …

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## [Testing assumptions for expected siblings' covariances](https://isgw-forum.colorado.edu/t/testing-assumptions-for-expected-siblings-covariances/311)

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**Author:** [@Giaco](https://isgw-forum.colorado.edu/u/Giaco)\
**Replies:** 2\
**Last updated:** [June 8, 2022, 7:00am UTC](https://isgw-forum.colorado.edu/t/testing-assumptions-for-expected-siblings-covariances/311 "2022-06-08T07:00:27Z")

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Testing assumptions for expected siblings’ covariances Hi. Inspired by the conversation of today and by the lecture of yesterday, I tried to figure out whether it was reasonable to assume, within the simulated dataset, …

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## [ACE Analyses of Categorical Variables Generated from a Mixture Model](https://isgw-forum.colorado.edu/t/ace-analyses-of-categorical-variables-generated-from-a-mixture-model/302)

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**Author:** [@srw7va](https://isgw-forum.colorado.edu/u/srw7va)\
**Replies:** 1\
**Last updated:** [June 7, 2022, 10:29pm UTC](https://isgw-forum.colorado.edu/t/ace-analyses-of-categorical-variables-generated-from-a-mixture-model/302 "2022-06-07T22:29:11Z")

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I am wondering if there are recommendations for conducting an ACE analysis on categorical data generated from a mixture model, such as a latent class growth model with individuals falling in Class\_1, Class\_2, or Class\_3.…

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## [Day 2 practical](https://isgw-forum.colorado.edu/t/day-2-practical/307)

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**Author:** [@katrina](https://isgw-forum.colorado.edu/u/katrina)\
**Replies:** 0\
**Last updated:** [June 7, 2022, 9:05pm UTC](https://isgw-forum.colorado.edu/t/day-2-practical/307 "2022-06-07T21:05:13Z")

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Day\_2\_Practical\_v2.pdf (1.4 MB) Here is a pdf of Day 2 practical.

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## [About the Slide 8 intuition behind the problem from The Direct Symmetric Matrix Approach to Fitting Twin Models](https://isgw-forum.colorado.edu/t/about-the-slide-8-intuition-behind-the-problem-from-the-direct-symmetric-matrix-approach-to-fitting-twin-models/299)

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**Author:** [@x.mo](https://isgw-forum.colorado.edu/u/x.mo)\
**Replies:** 1\
**Last updated:** [June 7, 2022, 1:21pm UTC](https://isgw-forum.colorado.edu/t/about-the-slide-8-intuition-behind-the-problem-from-the-direct-symmetric-matrix-approach-to-fitting-twin-models/299 "2022-06-07T13:21:24Z")

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Why the mean correlation between MZ is 0.5 and DZ is 0.25? I thought that was 1 in MZ and 0.5 in DZ.

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## [Session 2 Practical -- getting started](https://isgw-forum.colorado.edu/t/session-2-practical-getting-started/296)

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**Author:** [@katrina](https://isgw-forum.colorado.edu/u/katrina)\
**Replies:** 0\
**Last updated:** [June 7, 2022, 8:06am UTC](https://isgw-forum.colorado.edu/t/session-2-practical-getting-started/296 "2022-06-07T08:06:33Z")

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There are a number of R scripts and two data files that we will use in the Session 2 practical. To copy these files into your own area: Open the workshop SSH client Create a directory for the session (mkdir) mkdir day…
