# Day 1 **URL:** https://isgw-forum.colorado.edu/c/isg-workshops-2022/day-1/13.md [Latest](https://isgw-forum.colorado.edu/latest.md) · [Categories](https://isgw-forum.colorado.edu/categories.md) · [Tags](https://isgw-forum.colorado.edu/tags.md) --- ## [Day 1 practical instructions](https://isgw-forum.colorado.edu/t/day-1-practical-instructions/233)
**Author:** [@Elizabeth\_Prom-Worml](https://isgw-forum.colorado.edu/u/Elizabeth_Prom-Worml)\ **Replies:** 18\ **Last updated:** [June 8, 2022, 2:31am UTC](https://isgw-forum.colorado.edu/t/day-1-practical-instructions/233 "2022-06-08T02:31:57Z")
Hello All! Instructions for getting files for use on your workshop account are below. You are welcome to share any problems you are experiencing here in the forum and I will try to address as soon as possible. Make sur… --- ## [About the Day 1 category](https://isgw-forum.colorado.edu/t/about-the-day-1-category/33)
**Author:** [@JML](https://isgw-forum.colorado.edu/u/JML)\ **Replies:** 0
OpenMx, Path Analysis, Likelihood, Univariate ACE Model --- ## [Requirements for twin analysis](https://isgw-forum.colorado.edu/t/requirements-for-twin-analysis/531)
**Author:** [@handeezgia](https://isgw-forum.colorado.edu/u/handeezgia)\ **Replies:** 2\ **Last updated:** [March 20, 2023, 9:44am UTC](https://isgw-forum.colorado.edu/t/requirements-for-twin-analysis/531 "2023-03-20T09:44:33Z")
Hi! I am trying to run twin model by using my own dataset. However, the MZs correlations are not twice the size of Dz correlations. In this case, can I use twin modelling in my dataset? Example : Mz correlation for tra… --- ## [HWE and selection](https://isgw-forum.colorado.edu/t/hwe-and-selection/484)
**Author:** [@cpr2139](https://isgw-forum.colorado.edu/u/cpr2139)\ **Replies:** 2\ **Last updated:** [March 6, 2023, 10:33pm UTC](https://isgw-forum.colorado.edu/t/hwe-and-selection/484 "2023-03-06T22:33:34Z")
Is it ever possible that deviations from HWE are actually not a problem, but a signal of selection occurring for or against a phenotype? My intuition is that the kinds of timescales required to generate such a deviation … --- ## [OpenMx on ARM CPU](https://isgw-forum.colorado.edu/t/openmx-on-arm-cpu/375)
**Author:** [@Giaco](https://isgw-forum.colorado.edu/u/Giaco)\ **Replies:** 2\ **Last updated:** [July 3, 2022, 4:45pm UTC](https://isgw-forum.colorado.edu/t/openmx-on-arm-cpu/375 "2022-07-03T16:45:26Z")
Hi all, quick question on using OpenMx on ARM CPU: which optimizer do you recommend to use, since NPSOL is not supported on such architecture Installing OpenMx | OpenMx ? Will try to tag @michael.neale, but please let … --- ## [Creating a variable for a phenotype in each twin](https://isgw-forum.colorado.edu/t/creating-a-variable-for-a-phenotype-in-each-twin/373)
**Author:** [@pascaleac](https://isgw-forum.colorado.edu/u/pascaleac)\ **Replies:** 1\ **Last updated:** [June 28, 2022, 12:26am UTC](https://isgw-forum.colorado.edu/t/creating-a-variable-for-a-phenotype-in-each-twin/373 "2022-06-28T00:26:23Z")
I was reviewing the Day 1 script and noticed the variables, WT\_T1, and WT\_T2 describing the weight for twin 1 and twin 2. I am currently working with a dataset that does not include pre-calculated T1 and T2 variables fo… --- ## [Tracing Rules of Path Analysis](https://isgw-forum.colorado.edu/t/tracing-rules-of-path-analysis/316)
**Author:** [@xueyingqin](https://isgw-forum.colorado.edu/u/xueyingqin)\ **Replies:** 2\ **Last updated:** [June 9, 2022, 1:34am UTC](https://isgw-forum.colorado.edu/t/tracing-rules-of-path-analysis/316 "2022-06-09T01:34:59Z")
Hi, in page 6 of slides “Path analysis”, I would like to ask some questions about the tracing rules of path analysis. For the “rule a: Go backwards along single-headed arrows”, does it mean that the first step of tracin… --- ## [Answers to Day 1 Practical Are Posted](https://isgw-forum.colorado.edu/t/answers-to-day-1-practical-are-posted/315)
**Author:** [@Elizabeth\_Prom-Worml](https://isgw-forum.colorado.edu/u/Elizabeth_Prom-Worml)\ **Replies:** 0\ **Last updated:** [June 8, 2022, 2:27am UTC](https://isgw-forum.colorado.edu/t/answers-to-day-1-practical-are-posted/315 "2022-06-08T02:27:47Z")
Day 1 Practical answers are in /faculty/elizabeth/2022 look for file: Day 1 Practical ANSWERS.pdf --- ## [NPSOL is not available?](https://isgw-forum.colorado.edu/t/npsol-is-not-available/289)
**Author:** [@x.mo](https://isgw-forum.colorado.edu/u/x.mo)\ **Replies:** 3\ **Last updated:** [June 7, 2022, 2:31am UTC](https://isgw-forum.colorado.edu/t/npsol-is-not-available/289 "2022-06-07T02:31:07Z")
regFit ← mxRun( regModel, intervals=FALSE) Running Regression101 with 3 parameters Error in runHelper(model, frontendStart, intervals, silent, suppressWarnings, : NPSOL is not available in this build. See ?omx… --- ## [Path Analysis](https://isgw-forum.colorado.edu/t/path-analysis/283)
**Author:** [@oconnors](https://isgw-forum.colorado.edu/u/oconnors)\ **Replies:** 2\ **Last updated:** [June 7, 2022, 1:37am UTC](https://isgw-forum.colorado.edu/t/path-analysis/283 "2022-06-07T01:37:38Z")
Hello, In the video reviewing path analysis, why do we include VE when calculating the covariance in the ADE model? I had thought the covariance for MZ twins would be VA + VD and the covariance for DZ twins would be .5V… --- ## [ACE model](https://isgw-forum.colorado.edu/t/ace-model/284)
**Author:** [@Yahua\_Zi](https://isgw-forum.colorado.edu/u/Yahua_Zi)\ **Replies:** 1\ **Last updated:** [June 7, 2022, 12:17am UTC](https://isgw-forum.colorado.edu/t/ace-model/284 "2022-06-07T00:17:51Z")
For the ACE model, how could we get the standardized 95% CI values of A/C/E component effects? @Elizabeth\_Prom-Worml --- ## [Predefining input values](https://isgw-forum.colorado.edu/t/predefining-input-values/287)
**Author:** [@didi](https://isgw-forum.colorado.edu/u/didi)\ **Replies:** 1\ **Last updated:** [June 6, 2022, 10:34pm UTC](https://isgw-forum.colorado.edu/t/predefining-input-values/287 "2022-06-06T22:34:58Z")
Hi I have a question regarding defining the values while using the mxMatrix. How are these values calculated? For example in the script IntroToTwinAnalysisinRandOpenMx.R the starting values were defined as written belo… --- ## [Video on Eugenics Mentioned by Benjamin Neale](https://isgw-forum.colorado.edu/t/video-on-eugenics-mentioned-by-benjamin-neale/279)
**Author:** [@garree41](https://isgw-forum.colorado.edu/u/garree41)\ **Replies:** 1\ **Last updated:** [June 6, 2022, 6:09pm UTC](https://isgw-forum.colorado.edu/t/video-on-eugenics-mentioned-by-benjamin-neale/279 "2022-06-06T18:09:10Z")
Hello, Benjamin mentioned that Leah Davis gave a talk about the relationship between polygenicity and eugenics last year, where would I be able to find this? Thank you so much. --- ## [\[Questions about\] Accessing Code for Lectures](https://isgw-forum.colorado.edu/t/questions-about-accessing-code-for-lectures/225)
**Author:** [@spaul24](https://isgw-forum.colorado.edu/u/spaul24)\ **Replies:** 11\ **Last updated:** [June 6, 2022, 10:16am UTC](https://isgw-forum.colorado.edu/t/questions-about-accessing-code-for-lectures/225 "2022-06-06T10:16:41Z")
I am watching the lectures for Day 1 and would like to follow along with code as recommended in the videos. I have only been able to locate code for Day 0. Where can we find the code/files for Day 1 and subsequent days? …